Biopharmaceutical Chemical Compatibility

At International Filter Products Inc., we specialize in the sterile filtration of biological, pharmaceutical solutions, and various medications, understanding the critical importance of selecting filters that are chemically compatible with these specific applications. The success of filtration in these sensitive areas hinges on the right material choice, as incompatibilities can lead to compromised filter integrity and, consequently, non-sterile results.

Our chemical compatibility charts play a pivotal role in guiding you to the most suitable filter materials, ensuring they can withstand the specific chemical properties of your processes while maintaining the effectiveness of your filtration system.

We continually update our comprehensive guide to encompass a wide array of pharmaceutical solutions, and our team is always available to assist with unique or unlisted compounds. Leveraging our extensive expertise and diverse range of filter materials, we are committed to delivering effective and efficient bio-pharmaceutical filtration solutions tailored to your needs.

 

 

Chemical
(20°C, up to 24 hours)
Chemical Compatibility for Sterilizing Grade Membrane
Silicone O-rings Present No silicone O-rings Present
Z Series PES PES PTFE Z Series PES PES PTFE
Acetic acid Not Recommended Limited Limited Not Recommended Recommended Recommended
Acetone Not Recommended Not Recommended Not Recommended Not Recommended Not Recommended Recommended
Ammonium hydroxide Recommended Recommended Recommended Recommended Recommended Recommended
Benzyl alcohol Not Recommended Not Recommended Recommended Not Recommended Not Recommended Recommended
Boric acid 10% Recommended Recommended Recommended Recommended Recommended Recommended
Boric acid 5% Recommended Recommended Recommended Recommended Recommended Recommended
Carbon Tetrachloride (dry) Not Recommended Not Recommended Not Recommended Not Recommended Not Recommended Recommended
Carbon Tetrachloride (wet) Not Recommended Not Recommended Not Recommended Recommended Recommended Recommended
Chloroform Not Recommended Not Recommended Not Recommended Not Recommended Not Recommended Limited
Citric acid (concentrated) Limited Recommended Recommended Limited Recommended Recommended
Citric acid, 40% Recommended Recommended Recommended Recommended Recommended Recommended
Cyclohexanone Not Recommended Not Recommended Not Recommended Not Recommended Not Recommended Limited
Dimethyl sulfoxide (DMSO) Not Recommended Not Recommended Not Recommended Not Recommended Not Recommended Recommended
Ethyl acetate Recommended Recommended Recommended Recommended Recommended Recommended
Ethylene glycol Recommended Recommended Recommended Recommended Recommended Recommended
Formaldehyde Limited Limited Limited Limited Recommended Recommended
Glycerol Recommended Recommended Recommended Recommended Recommended Recommended
Hexane Not Recommended Not Recommended Not Recommended Recommended Recommended Recommended
Hydrochloric acid Not Recommended Not Recommended Not Recommended Recommended Recommended Recommended
Hydrogen peroxide, < 90% Not Recommended Limited Limited Not Recommended Recommended Recommended
Isopropyl alcohol (IPA) Limited Recommended Recommended Limited Recommended Recommended
Isobutyl alcohol Recommended Recommended Recommended Recommended Recommended Recommended
Methanol Not Recommended Not Recommended Not Recommended Limited Recommended Recommended
Nitric acid, 60% Not Recommended Not Recommended Not Recommended Not Recommended Not Recommended Not Recommended
Ozone Not Recommended Not Recommended Not Recommended Not Recommended Not Recommended Not Recommended
Phenol, 10% Not Recommended Not Recommended Not Recommended Not Recommended Limited Recommended
Phosphoric acid (aerated) Not Recommended Not Recommended Not Recommended Limited Limited Limited
Phosphoric acid (air free) Not Recommended Not Recommended Not Recommended Limited Limited Limited
Potassium hydroxide Limited Recommended Recommended Limited Recommended Recommended
Pyridine Not Recommended Not Recommended Not Recommended Not Recommended Not Recommended Recommended
Sodium hydroxide Not Recommended Limited Limited Not Recommended Recommended Recommended
Sodium hypochlorite Limited Recommended Recommended Limited Recommended Recommended
Sulfuric acid (aerated) Not Recommended Not Recommended Not Recommended Not Recommended Not Recommended Limited
Sulfuric acid (air free) Not Recommended Not Recommended Not Recommended Not Recommended Not Recommended Limited
Tetrahydrofuran (THF) Not Recommended Not Recommended Not Recommended Not Recommended Not Recommended Limited
Urea Not Recommended Not Recommended Recommended Not Recommended Not Recommended Recommended

Still have questions?

We're here to help. You can reach out to us so we can help answer any questions you have.